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NFIC Antibody (PA5-90204) in WB
Western blot analysis of NFIC in extracts of various cell lines. Samples were incubated with NFIC Polyclonal antibody (Product # PA5-90204) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
产品信息
PA5-90204
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human NFIC (NP_0055882)
偶联物
形式
Liquid
浓度
2.16 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2805958
产品详细信息
Immunogen sequence: MYSSPLCLTQ DEFHPFIEAL LPHVRAFAYT WFNLQARKRK YFKKHEKRMS KDEERAVKDE LLGEKPEVKQ KWASRLLAKL RKDIRPECRE DFVLSITGKK APGCVLSNPD QKGKMRRIDC LRQADKVWRL DLVMVILFKG IPLESTDGER LVKAAQCGHP VLCVQPHHIG VAVKELDLYL AYFVRERDAE QSGSPRTGMG SDQEDSKPIT LDTTDFQESF; Positive Samples: HeLa, LO2, MCF-7, DU145, NIH/3T3, mouse liver, mouse skeletal muscle, rat liver; Cellular Location: Nucleus
靶标信息
Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: CCAAT-box-binding transcription factor; CTF; KIAA1439; NF-I/A; NF-I/B; NF-I/C; NF-I/X; NF1-A; NF1-B; NF1-C; NF1-X; NFI-A; NFI-B; NFI-C; NFI-X; NFIA; NFIB; NFIX; Nuclear factor 1 C-type; nuclear factor 1-C2; Nuclear factor 1/A; Nuclear factor 1/B; nuclear factor 1/C; Nuclear factor 1/X; Nuclear factor I/A; Nuclear factor I/B; Nuclear factor I/C; nuclear factor I/C (CCAAT-binding transcription factor); Nuclear factor I/X; olfactory epithelium nuclear factor I-C; TGGCA-binding protein
基因别名: 1110019L22Rik; 1500041O16Rik; AA589446; AI746521; CTF; CTF5; NF-I; NF1-C; NFI; NFIC
UniProt ID: (Human) P08651, (Mouse) P70255
Entrez Gene ID: (Human) 4782, (Mouse) 18029, (Rat) 29228
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter proximal region DNA binding
DNA binding
double-stranded DNA binding
protein binding
DNA-binding transcription factor
gene-specific transcriptional regulator
negative regulation of transcription from RNA polymerase II promoter
DNA replication
transcription from RNA polymerase II promoter
odontogenesis of dentin-containing tooth
positive regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
negative regulation of transcription, DNA-templated
sensory perception of smell
