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产品信息
H00004784-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
NFIX (NP_002492, 1 a.a. approximately 441 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MYSPYCLTQD EFHPFIEALL PHVRAFSYTW FNLQARKRKY FKKHEKRMSK DEERAVKDEL LGEKPEIKQK WASRLLAKLR KDIRPEFRED YVLTITGKKP PCCVLSNPDQ KGKIRRIDCL RQADKVWRLD LVMVILFKGI PLESTDGERL YKSPQCSNPG LCVQPHHIGV TIKELDLYLA YFVHTPESGQ SDSSNQQGDA DIKPLPNGHL SFQDCFVTSG VWNVTELVRV SQTPVATASG PNFSLADLES PSYYNINQVT LGRRSITSPP STSTTKRPKS IDDSEMESPV DDVFYPGTGR SPAAGSSQSS GWPNDVDAGP ASLKKSGKLD FCSALSSQGS SPRMAFTHHP LPVLAGVRPG SPRATASALH FPSTSIIQQS SPYFTHPTIR YHHHHGQDSL KEFVQFVCSD GSGQATGQHS QRQAPPLPTG LSASDPGTAT F
靶标信息
NF-1, also designated CTF, consists of a family of CCAAT box binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA binding domain, and activates transcription through a putatively novel, proline-rich, carboxy terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, including that of Ha-Ras, alpha-globin, HSP 70, GRP 78, Histone H1, myelin basic protein and in the Xenopus laevis vitellogenin gene promoter.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CCAAT-binding transcription factor; CCAAT-box-binding transcription factor; CTF; KIAA1439; NF-I/A; NF-I/B; NF-I/C; NF-I/X; NF1-A; NF1-B; NF1-C; NF1-X; NFI; NFI-A; NFI-B; NFI-C; NFIA; NFIB; NFIC; Nuclear factor 1 X-type; Nuclear factor 1/A; Nuclear factor 1/B; Nuclear factor 1/C; nuclear factor 1/X; Nuclear factor I/A; Nuclear factor I/B; Nuclear factor I/C; Nuclear factor I/X; nuclear factor I/X (CCAAT-binding transcription factor); TGGCA-binding protein
基因别名: MRSHSS; NF1A; NFIX; SOTOS2
UniProt ID: (Human) Q14938
Entrez Gene ID: (Human) 4784
