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This target displays homology in the following species: Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%
This gene encodes a magnesium transporter that associates with early endosomes and the cell surface in a variety of neuronal and epithelial cells. This protein may play a role in nervous system development and maintenance. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with autosomal dominant spastic paraplegia 6.
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Protein Aliases: Magnesium transporter NIPA1; non-imprinted in Prader-Willi/Angelman syndrome 1; Non-imprinted in Prader-Willi/Angelman syndrome region protein 1; Spastic paraplegia 6 protein
Gene Aliases: FSP3; NIPA1; SPG6
UniProt ID: (Human) Q7RTP0
Entrez Gene ID: (Human) 123606
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