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Product Details
PA5-58315
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human NIPA4. Recombinant protein control fragment (Product #RP-96939).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2644687
Product Specific Information
Immunogen sequence: FKDLDISCAS LPHMHKNPPP SPAPEPTVIR LEDKNVLVDN IELASTSSPE EKPKVFIIHS
Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 82%.
Target Information
NIPAL4 acts as a Mg(2+) transporter and can also transport other divalent cations such as Ba(2+), Mn(2+), Sr(2+) and Co(2+) but to a much less extent than Mg(2+). NIPAL4 may also be a receptor for ligands (trioxilins A3 and B3) from the hepoxilin pathway. The NIPAL4 gene likely encodes a membrane receptor. Mutations in the NIPAL4 gene have been associated with autosomal recessive congenital ichthyosis. Diseases associated with NIPAL4 include Ichthyosis, Congenital, Autosomal Recessive 6 and Autosomal Recessive Congenital Ichthyosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ichthyin; Magnesium transporter NIPA4; NIPA-like domain containing 4; NIPA-like protein 4; Non-imprinted in Prader-Willi/Angelman syndrome region protein 4
Gene Aliases: ARCI6; ICHN; ICHTHYIN; ICHYN; NIPA4; NIPAL4
UniProt ID: (Human) Q0D2K0
Entrez Gene ID: (Human) 348938
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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