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NIPAL4 (extracellular) Antibody (ANT-144-200UL) in WB
Western blot analysis of human acute monocytic leukemia cell line THP-1 (lanes 1 and 2), mouse Bcelllymphoma cell line WEHI-231 (lanes 3 and 4), rat brain membranes (lanes 5 and 7) and mouse brain membranes (lanes 6 and 8): - 1,3,5,7. Anti-NIPAL4 (extracellular) Antibody (#ANT-144), (1:400).2,4,6,8. Anti-NIPAL4 (extracellular) Antibody , preincubated with NIPAL4 (extracellular) Blocking Peptide (#BLP-NT144)... View More
Product Details
ANT-144-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)EKVTTIMEMASKMKD, corresponding to amino acid residues 242-256 of human magnesium transporter NIPA4, 2nd extracellular loop
Conjugate
Form
Lyophilized
Concentration
0.85 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
NIPAL4 acts as a Mg(2+) transporter and can also transport other divalent cations such as Ba(2+), Mn(2+), Sr(2+) and Co(2+) but to a much less extent than Mg(2+). NIPAL4 may also be a receptor for ligands (trioxilins A3 and B3) from the hepoxilin pathway. The NIPAL4 gene likely encodes a membrane receptor. Mutations in the NIPAL4 gene have been associated with autosomal recessive congenital ichthyosis. Diseases associated with NIPAL4 include Ichthyosis, Congenital, Autosomal Recessive 6 and Autosomal Recessive Congenital Ichthyosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ichthyin; Magnesium transporter NIPA4; NIPA-like domain containing 4; NIPA-like protein 4; Non-imprinted in Prader-Willi/Angelman syndrome region protein 4; Non-imprinted in Prader-Willi/Angelman syndrome region protein 4 homolog
Gene Aliases: 9530066K23Rik; ARCI6; ICHN; ICHTHYIN; ICHYN; NIPA4; NIPAL4; RGD1309452
UniProt ID: (Human) Q0D2K0, (Mouse) Q8BZF2
Entrez Gene ID: (Human) 348938, (Mouse) 214112, (Rat) 303070
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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