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Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha-ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively. Overexpression decreases the colony-forming capacity of cultured cells by arresting cells in the G2 phase of the cell cycle.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: epididymis secretory sperm binding protein Li 8a; Nit protein 2; nitrilase family, member 2; Nitrilase homolog 2; Omega-amidase NIT2
基因别名: 1190017B19Rik; CUA002; D16Ertd502e; HEL-S-8a; NIT2
UniProt ID: (Human) Q9NQR4, (Mouse) Q9JHW2
Entrez Gene ID: (Human) 56954, (Mouse) 52633