Invitrogen

NKG2A Polyclonal Antibody

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NKG2A Antibody (PA5-88485) in WB

Western blot analysis of NKG2A in extracts of various cell lines. Samples were incubated with NKG2A Polyclonal antibody (Product # PA5-88485) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 5 min.

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产品信息

PA5-88485

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

酶联免疫吸附实验 (ELISA)

1 µg/mL

产品规格

种属反应

Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fusion protein containing a sequence corresponding to amino acids 96-215 of human KLRC1 (NP_0155671)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.53 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

RRID

AB_2804945

产品详细信息

Immunogen sequence: RHCGHCPEEW ITYSNSCYYI GKERRTWEES LLACTSKNSS LLSIDNEEEM KFLSIISPSS WIGVFRNSSH HPWVTMNGLA FKHEIKDSDN AELNCAVLQV NRLKSAQCGS SIIYHCKHKL; Positive Samples: Mouse testis, Mouse liver; Cellular Location: Membrane, Single-pass type II membrane protein

靶标信息

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.

仅用于科研。不用于诊断过程。未经明确授权不得转售。