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A murine NKX2-8 was isolated from the Hepal-6 cell line and showed oligonucleotide binding competitive with fetoprotein transcription factor. Nkx2.8 bound to the active AFP promoter, and antisense inhibition of Nkx2.8 mRNA translation selectively reduced expression of both the endogenous human AFP gene and transfected reporters containing the rat AFP promoter.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Homeobox protein NK-2 homolog H; Homeobox protein Nkx-2.8; NK-2 homolog 8; NK-2 homolog H; NK2 transcription factor related, locus 8
基因别名: NKX-2.8; NKX2-8; Nkx2-9; NKX2.8; NKX2G; NKX2H
UniProt ID: (Human) O15522
Entrez Gene ID: (Human) 26257