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NKX6-2 Antibody (PA5-48988) in WB
Western blot analysis of NKX6-2 in K562 whole cell lysate. Samples were incubated with NKX6-2 polyclonal antibody (Product # PA5-48988) using a dilution of 1:1,000 followed by Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at a dilution of 1:10,000. Lysates/proteins: 20 µg per lane. Predicted band size: 29 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
产品信息
PA5-48988
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 17-43 amino acids from the N-terminal region of human NKX6-2.
偶联物
形式
Liquid
浓度
0.45 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2634444
靶标信息
Transcription factor with repressor activity involved in the regulation of axon-glial interactions at myelin paranodes in oligodendrocytes. Binds to the consensus DNA sequence 5'-(A/T)TTAATGA-3'. In oligodendrocytes, binds to MBP and PLP1 promoter regions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: glial and testis-specific homeobox protein; homeobox 6B; Homeobox protein NK-6 homolog B; Homeobox protein Nkx-6.2; NK homeobox family 6, B; NK6 transcription factor related, locus 2
基因别名: GTX; NKX6-2; NKX6.2; NKX6B
UniProt ID: (Human) Q9C056
Entrez Gene ID: (Human) 84504
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
negative regulation of cell fate commitment
positive regulation of cell fate commitment
regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification
regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification
central nervous system myelination
endocrine pancreas development
negative regulation of glial cell differentiation
positive regulation of glial cell differentiation
neuromuscular process controlling balance
