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产品信息
A305-717A
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A region between residue 100 to 150 of human Notchless protein homolog 1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
phosphate/tris citrate, pH 7.0 to 8.0
内含物
0.09% sodium azide
保存条件
4° C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Predicted reactivity by homology: Orangutan, Bovine.
靶标信息
NLE1 plays a role in regulating Notch activity, in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its effects on Notch activity. NLE1 is required during embryogenesis for inner mass cell survival.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ10458; Notchless gene homolog; Notchless protein homolog 1; novel WD40 repeat containing protein
基因别名: AL022765; BC018399; HUSSY-07; l11Jus1; l11Jus4; Nle; NLE1
UniProt ID: (Human) Q9NVX2, (Mouse) Q8VEJ4
Entrez Gene ID: (Human) 54475, (Mouse) 217011
somitogenesis
kidney development
inner cell mass cell differentiation
Notch signaling pathway
ribosomal large subunit biogenesis
negative regulation of mitotic cell cycle
skeletal system morphogenesis
hematopoietic stem cell homeostasis
positive regulation of canonical Wnt signaling pathway
negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
