Invitrogen

NLRX1 Polyclonal Antibody

NLRX1 Antibody in Immunocytochemistry (ICC/IF)

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NLRX1 Antibody (PA5-118121) in ICC/IF

Immunofluorescence staining of NLRX1 in A549 cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with NLRX1 Polyclonal Antibody (Product # PA5-118121, 1:200) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to cytoplasm.

NLRX1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

NLRX1 Antibody in Immunoprecipitation (IP)

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产品信息

PA5-118121

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

免疫组化（石蜡） (IHC (P))

1:50-1:200

免疫细胞化学 (ICC/IF)

1:100-1:500

免疫沉淀 (IP)

1-5 µL/mg of lysate

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

E. coli-derived Human NLRX1 fragment

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

纯化类型

Antigen affinity chromatography, Protein A

保存液

PBS, pH 7

内含物

0.03% ProClin 300

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

AB_2902721

靶标信息

This gene encodes a member of the NLR family. Alternative splicing has been observed at this gene locus and two transcript variants, encoding distinct isoforms, have been identified.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Caterpiller protein 11.3; CLR11.3; FLJ21478; MGC131937; MGC21025; NLR family member X1; NOD-like receptor X1; nucleotide-binding oligomerization domain protein 26; Nucleotide-binding oligomerization domain protein 5; Nucleotide-binding oligomerization domain protein 9; nucleotide-binding oligomerization domain, leucine rich repeat containing X1; OTTHUMP00000205768; OTTHUMP00000205769

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基因别名: CLR11.3; DLNB26; NLRX1; NOD26; NOD5; NOD9

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UniProt ID: (Human) Q86UT6

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Entrez Gene ID: (Human) 79671

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功能

protein binding ATP binding scaffold/adaptor protein

参与通路

viral process negative regulation of type I interferon production negative regulation of interferon-beta production negative regulation of interleukin-6 production negative regulation of RIG-I signaling pathway negative regulation of I-kappaB kinase/NF-kappaB signaling innate immune response negative regulation of innate immune response negative regulation of inflammatory response