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产品信息
PA5-100291
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human NMD3(Accession Q96D46), corresponding to amino acid residues L385-D435.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2849805
产品详细信息
Antibody detects endogenous levels of total NMD3.
靶标信息
NMD3 is a cytoplasmic factor required for a late cytoplasmic assembly step of the 60S subunit but is not a ribosomal protein. A mutation in NMD3 was found to be lethal in the absence of XRN1, which encodes the major cytoplasmic exoribonuclease responsible for mRNA turnover. The NMD3 protein sequence does not contain readily recognizable motifs of known function. However, NMD3 orthologues display an amino-terminal domain containing four repeats of Cx2C, reminiscent of zinc-binding proteins, implicated in nucleic acid binding or protein oligomerization.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 60S ribosomal export protein NMD3; hNMD3; NMD3 homolog
基因别名: C87860; CGI-07; NMD3; RGD1308468
UniProt ID: (Human) Q96D46, (Mouse) Q99L48
Entrez Gene ID: (Human) 51068, (Mouse) 97112, (Rat) 310512
