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NME4 Antibody (PA5-78081) in IHC (P)
nm23-H4 antibody detects nm23-H4 protein at cytosol on mouse hind brain by immunohistochemical analysis. Sample: Paraffin-embedded mouse hind brain. Nm23-H4 antibody (Product # PA5-78081) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
产品信息
PA5-78081
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human NME4. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2736239
产品详细信息
Positive Control: human NME4-transfected 293T cells
Predicted Reactivity: Xenopus laevis (80%), Pig (90%), Rhesus Monkey (99%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
NME4 is a protein kinases, which are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: expressed in non-metastatic cells 4, protein; NDK; NDP kinase D; NDP kinase, mitochondrial; NDPKD; nm23-H4; nm23-M4; non-metastatic cells 4, protein expressed in; nucleoside diphosphate kinase 4; Nucleoside diphosphate kinase D; Nucleoside diphosphate kinase, mitochondrial
基因别名: 2610027N22Rik; 2810024O08Rik; 5730493H09Rik; NDPK-D; nm23-H4; NM23-M4; NM23D; NM23H4; Nm23M4; NME4
UniProt ID: (Human) O00746, (Mouse) Q9WV84
Entrez Gene ID: (Human) 4833, (Rat) 685679, (Mouse) 56520
purine nucleotide metabolic process
nucleoside diphosphate phosphorylation
GTP biosynthetic process
pyrimidine nucleotide metabolic process
UTP biosynthetic process
CTP biosynthetic process
lipid transport
nucleoside metabolic process
nucleoside triphosphate biosynthetic process
nucleobase-containing small molecule interconversion
regulation of apoptotic process
nucleotide metabolic process
phosphorylation
