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NME5 Antibody (PA5-145309) in IHC (P)
Immunohistochemistry (Paraffin) analysis of NME5 in Human Kidney Tissue. Samples were incubated in NME5 polyclonal antibody (Product # PA5-145309) using a dilution of 20 µg/mL followed by HRP-Linked Caprine Anti-Rabbit IgG at a dilution of 2 µg/mL and DAB staining.
产品信息
PA5-145309
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human NME5 protein, Ile3-Lys194 (Accession #P56597)
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.05% Proclin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_3093539
靶标信息
Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3'-5' exonuclease NME5; expressed in non-metastatic cells 5; Inhibitor of p53-induced apoptosis-beta; IPIA-beta; NDK-H 5; NDP kinase homolog 5; nm23-H5; nm23-M5; NME/NM23 family member 5; non-metastatic cells 5 protein expressed in; non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase); Nucleoside diphosphate kinase homolog 5; radial spoke 23 homolog; Rsph23; Testis-specific nm23 homolog
基因别名: 1700019D05Rik; NM23-H5; Nm23-M5; NM23H5; NME5; RSPH23
UniProt ID: (Human) P56597, (Mouse) Q99MH5
Entrez Gene ID: (Human) 8382, (Mouse) 75533, (Rat) 688903
epithelial cilium movement
nucleoside diphosphate phosphorylation
GTP biosynthetic process
UTP biosynthetic process
CTP biosynthetic process
spermatogenesis
spermatid development
nucleoside metabolic process
ventricular system development
cilium assembly
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
response to reactive oxygen species
multicellular organism development
cell differentiation
spermatid differentiation
