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Antibody detects endogenous levels of total NMNAT2.
Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate but with a lower efficiency. Cannot use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity prefers NAD(+), NADH and NAAD as substrates and degrades nicotinic acid adenine dinucleotide phosphate (NHD) less effectively. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NAADP(+).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Blad; naMN adenylyltransferase 1; NaMN adenylyltransferase 2; Nicotinamide mononucleotide adenylyltransferase 2; Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2; nicotinate-nucleotide adenylyltransferase 1; Nicotinate-nucleotide adenylyltransferase 2; NMN adenylyltransferase 2; NMN/NaMN adenylyltransferase 2; Protein bloated bladder; pyridine nucleotide adenylyltransferase 2
基因别名: AI843915; C1orf15; D030041I09Rik; KIAA0479; NMNAT2; PNAT1; PNAT2
UniProt ID: (Human) Q9BZQ4, (Mouse) Q8BNJ3, (Rat) Q0HA29
Entrez Gene ID: (Human) 23057, (Mouse) 226518, (Rat) 289095