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This target displays homology in the following species: Cow: 86%; Guinea Pig: 93%; Horse: 93%; Human: 93%; Mouse: 100%; Rabbit: 86%; Rat: 100%
NOR-1, a NR4 nerve growth factor-like receptor, has been shown to affect neuronal development, T-cell apoptosis, and cancer development. NOR-1 binds to NBRE (NGFI-B response element) and regulates the pro-opiomelanocortin (POMC) gene. NOR-1 is induced rapidly but transiently by a variety of stimuli. Downregulation of NOR-1 and other NGFI-B family members is correlated with drug addiction-prone behavior of Lewis rats. Three human protein isoforms have been documented: NOR-1, NOR-1beta, and NOR-1 3' variant.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Nuclear receptor subfamily 4 group A member 3; Orphan nuclear receptor TEC; TEC receptor; Translocated in extraskeletal chondrosarcoma
基因别名: AI573420; CHN; CSMF; MINOR; NOR-1; Nor1; Nr4a3; TEC
UniProt ID: (Mouse) Q9QZB6
Entrez Gene ID: (Mouse) 18124