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产品信息
PA5-96588
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 661-765 of human NOX5 (NP_0787813)
偶联物
形式
Liquid
浓度
1.6 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2808390
产品详细信息
Positive Samples: 22Rv1; Cellular Location: Endoplasmic reticulum, Membrane, Multi-pass membrane protein
Immunogen sequence: AEEAQYGRFL ELHMYMTSAL GKNDMKAIGL QMALDLLANK EKKDSITGLQ TRTQPGRPDW SKVFQKVAAE KKGKVQVFFC GSPALAKVLK GHCEKFGFRF FQENF
靶标信息
This gene is predominantly expressed in the testis and lymphocyte-rich areas of spleen and lymph nodes. It encodes a calcium-dependen NADPH oxidase that generates superoxide, and functions as a calcium-dependent proton channel that may regulate redox-dependent processes in lymphocytes and spermatozoa. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011].
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生物信息学
response to reactive oxygen species
cytokinesis
angiogenesis
endothelial cell proliferation
apoptotic process
cell proliferation
regulation of proton transport
proton transport
superoxide anion generation
regulation of fusion of sperm to egg plasma membrane
cytokine secretion
oxidation-reduction process
