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产品信息
PA5-51988
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human NPNT. Recombinant protein control fragment (Product #RP-101074).
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2644775
产品详细信息
Immunogen sequence: RQCVNTFGSY ICKCHKGFDL MYIGGKYQCH DIDECSLGQY QCSSFARCYN VRGSYKCKCK EGYQGDGLTC VYIPKVMIEP SGPIHVPKGN GTILKGDTGN NNWIPDVGST WWPPKTPYIP PIITNRPTSK PTTRPTPK
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 54%.
靶标信息
Functional ligand of integrin alpha-8/beta-1 in kidney development. Regulates the expression of GDNF with integrin alpha-8/beta-1 which is essential for kidney development. May also play a role in the development and function of various tissues, regulating cell adhesion, spreading and survival through the binding of several integrins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Nephronectin; Preosteoblast EGF-like repeat protein with MAM domain; Protein EGFL6-like
基因别名: EGFL6L; NPNT; POEM; UNQ295/PRO334
UniProt ID: (Human) Q6UXI9
Entrez Gene ID: (Human) 255743
ureteric bud development
branching involved in ureteric bud morphogenesis
cell-matrix adhesion
positive regulation of alkaline phosphatase activity
positive regulation of cell-substrate adhesion
extracellular matrix organization
positive regulation of transforming growth factor beta receptor signaling pathway
cell-cell adhesion mediated by integrin
establishment of protein localization
positive regulation of osteoblast differentiation
positive regulation of smooth muscle contraction
positive regulation of ERK1 and ERK2 cascade
cellular response to tumor necrosis factor
pilomotor reflex
positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation
