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NPY2R Antibody (PA5-102110) in ICC/IF
Immunofluorescent analysis of NPY2R in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% saponin, blocked with 10% serum (45 min at 25°C) incubated with NPY2R polyclonal antibody (Product # PA5-102110) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) at a dilution of 1:600.
Product Details
PA5-102110
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human NPY2R(Accession P49146), corresponding to amino acid residues D9-S59.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2851537
Product Specific Information
Antibody detects endogenous levels of total NPY2R.
Target Information
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC124241; MGC124242; MGC124244; Neuropeptide Y receptor type 2; neuropeptide Y receptor Y2-like; Neuropeptide y-y2; neuropeptide Y-Y2 receptor; neuropeptide Y/peptide YY-Y2 receptor; NPY-Y2 receptor; NPY2-R; Y2 receptor
Gene Aliases: NPY2-R; NPY2R
UniProt ID: (Human) P49146, (Mouse) P97295
Entrez Gene ID: (Human) 4887, (Mouse) 18167, (Rat) 66024
behavioral fear response
positive regulation of peptide secretion
outflow tract morphogenesis
cardiac left ventricle morphogenesis
cell surface receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
neuropeptide signaling pathway
nitric oxide mediated signal transduction
chemical synaptic transmission
locomotory behavior
feeding behavior
positive regulation of cell-substrate adhesion
negative regulation of cAMP biosynthetic process
negative regulation of neurological system process
positive regulation of dopamine secretion
positive regulation of smooth muscle contraction
positive regulation of circadian sleep/wake cycle, non-REM sleep
secretion
negative regulation of secretion
regulation of sensory perception of pain
negative regulation of synaptic transmission, glutamatergic
negative regulation of excitatory postsynaptic potential
negative regulation of feeding behavior
signal transduction
G-protein coupled receptor signaling pathway
negative regulation of synaptic transmission
positive regulation of cell adhesion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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