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NR1D2 Antibody (H00009975-D01P) in WB
Western Blot analysis of NR1D2 expression in transfected 293T cell line (H00009975-T02) by NR1D2 MaxPab polyclonal antibody.
Lane 1: NR1D2 transfected lysate(64.70 KDa).
Lane 2: Non-transfected lysate.
Lane 1: NR1D2 transfected lysate(64.70 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00009975-D01P
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
NR1D2 (NP_005117.2, 1 a.a. approximately 579 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MEVNAGGVIA YISSSSSASS HASCHSEGSE NSFQSSSSSV PSSPNSSNSD TNGNPKNGDL ANIEGILKND RIDCSMKTSK SSAPGMTKSH SGVTKFSGMV LLCKVCGDVA SGFHYGVHAC EGCKGFFRRS IQQNIQYKKC LKNENCSIMR MNRNRCQQCR FKKCLSVGMS RDAVRFGRIP KREKQRMLIE MQSAMKTMMN SQFSGHLQND TLVEHHEQTA LPAQEQLRPK PQLEQENIKS SSPPSSDFAK EEVIGMVTRA HKDTFMYNQE QQENSAESMQ PKRGERIRKN MEQYNLNHDH CGNGLSSHFP CSESQQHLNG QFKGRNIMHY PNGHAICIAN GHCMNFSNAY TQRVCDRVPI DGFSQNENKN SYLCNTGGRM HLVCPMSKSP YVDPHKSGHE IWEEFSMSFT PAVKEVVEFA KRIPGFRDLS QHDQVNLLKA GTFEVLMVRF ASLFDAKERT VTFLSGKKYS VDDLHSMGAG DLLNSMFEFS EKLNALQLSD EEMSLFTAVV LVSADRSGIE NVNSVEALQE TLIRALRTLI MKNHPNEASI FTKLLLKLPD LRSLNNMHSE ELLAFKVHP
靶标信息
This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EAR-1R; HZF2; nuclear receptor Rev-ErbA beta variant 1; nuclear receptor Rev-ErbA beta variant 2; Nuclear receptor subfamily 1 group D member 2; nuclear receptor subfamily 1, group D, member 2; Orphan nuclear hormone receptor BD73; Orphan nuclear receptor RVR; Rev-erb alpha-related receptor; Rev-erb beta; Rev-erb-beta; Rev-erba beta; rev-erba-alpha-related receptor; Rev-erbabeta; RVR; V-erbA-related protein 1-related
基因别名: BD73; EAR-1R; NR1D2; Rev-erb; RVR
UniProt ID: (Human) Q14995, (Mouse) Q60674
Entrez Gene ID: (Human) 9975, (Mouse) 353187
core promoter sequence-specific DNA binding
steroid hormone receptor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
zinc ion binding
DNA binding
transcription factor activity, sequence-specific DNA binding
thyroid hormone receptor activity
sequence-specific DNA binding
metal ion binding
C4 zinc finger nuclear receptor
DNA-binding transcription factor
zinc finger transcription factor
gene-specific transcriptional regulator
regulation of transcription, DNA-templated
transcription initiation from RNA polymerase II promoter
regulation of lipid metabolic process
intracellular receptor signaling pathway
regulation of circadian rhythm
steroid hormone mediated signaling pathway
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
rhythmic process
regulation of inflammatory response
lipid homeostasis
regulation of energy homeostasis
regulation of skeletal muscle cell differentiation
transcription, DNA-templated
