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产品信息
PA5-32948
产品规格
种属反应
Bat,
Bovine,
Dog,
Chicken,
Horse,
Human,
Mouse,
Non-human primate,
Rabbit,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 16 amino acid peptide from internal region of human NR1D2.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2550409
产品详细信息
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Bat, Panda, Horse, Rabbit, Turkey, Chicken (100%); Elephant, Platypus (94%); Opossum, Xenopus (81%).
For IHC(P), use proteinase K antigen retrieval. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
靶标信息
This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EAR-1R; EAR4; HZF2; nuclear receptor Rev-ErbA beta variant 1; nuclear receptor Rev-ErbA beta variant 2; Nuclear receptor subfamily 1 group D member 2; Nuclear receptor subfamily 1 group D member 2-like protein; nuclear receptor subfamily 1, group D, member 2; Orphan nuclear hormone receptor BD73; orphan nuclear receptor HZF-2; Orphan nuclear receptor RVR; orphan receptor; Rev-erb alpha-related receptor; Rev-erb beta; Rev-erb-beta; Rev-erb-Beta2; Rev-erba beta; rev-erba-alpha-related receptor; Rev-ErbA-beta; Rev-erbabeta; REV-ERBb; RVR; V-erbA-related protein 1-related
基因别名: BD73; EAR-1R; HZF-2; NR1D2; Rev-erb; REV-ERBB; RVR
UniProt ID: (Human) Q14995, (Mouse) Q60674, (Rat) Q63504
Entrez Gene ID: (Rabbit) 100349421, (Human) 9975, (Horse) 100060122, (Dog) 485643, (Bovine) 532076, (Chicken) 396125, (Mouse) 353187, (Rat) 259241
core promoter sequence-specific DNA binding
steroid hormone receptor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
zinc ion binding
DNA binding
transcription factor activity, sequence-specific DNA binding
thyroid hormone receptor activity
sequence-specific DNA binding
metal ion binding
C4 zinc finger nuclear receptor
DNA-binding transcription factor
zinc finger transcription factor
gene-specific transcriptional regulator
regulation of transcription, DNA-templated
transcription initiation from RNA polymerase II promoter
regulation of lipid metabolic process
intracellular receptor signaling pathway
regulation of circadian rhythm
steroid hormone mediated signaling pathway
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
rhythmic process
regulation of inflammatory response
lipid homeostasis
regulation of energy homeostasis
regulation of skeletal muscle cell differentiation
transcription, DNA-templated
