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产品信息
H00007182-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
NR2C2 (AAH51670.1, 1 a.a. approximately 530 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MTSPSPRIQI ISTDSAVASP QRIQGSEPAS GPLSVFTSLN KEKIVTDQQT GQKIQIVTAV DASGSPKQQF TLTSPDGAGT GKVILASPET SSAKQLIFTT SDNLVPGRIQ IVTDSASVER LLGKTDVQRP QVVEYCVVCG DKASGRHYGA VSCEGCKGFF KRSVRKNLTY SCRSNQDCII NKHHRNRCQF CRLKKCLEMG MKMESVQSKR KPFDVQREKP SNCAASTEKI YIRKDLRSPL IATPTFVADK DGARQTGLLD PGMLVNIQQP LIREDGTVLL ATDSKAETSQ GALGTLANVV TSLANLSESL NNGDTSEIQP EDQSASEITR AFDTLAKALN TTDSSSSPSL ADGIDTSGGG SIHVISRDQS TPIIEVEGPL LSDTHVTFKL TMPSPMPEYL NVHYICESAS RLLFLSMHWA RSIPAFQALG QDCNTSLVRA CWNELFTLGL AQCAQVMSLS TILAAIVNHL QNSIQEDKLS GDRIKQVMEH IWKLQEFCNS MAKLDIDGYE YAYLKAIVLF SPGKICGGDA
靶标信息
Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Nuclear hormone receptor TR4; Nuclear receptor subfamily 2 group C member 2; nuclear receptor subfamily 2, group C, member 2; Orphan nuclear receptor TAK1; Orphan nuclear receptor TR4; orphan receptor TR4; testicular nuclear receptor 4; Testicular receptor 4; TR2R1
基因别名: NR2C2; TAK1; TR4
UniProt ID: (Human) P49116
Entrez Gene ID: (Human) 7182
regulation of transcription, DNA-templated
transcription initiation from RNA polymerase II promoter
spermatogenesis
nervous system development
cerebellum development
cell differentiation
p38MAPK cascade
positive regulation of embryonic development
steroid hormone mediated signaling pathway
positive regulation of myoblast differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of behavior
meiotic cell cycle
mitophagy in response to mitochondrial depolarization
