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产品信息
PA5-21611
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to a region within amino acids 1 and 44 of COUP TF1 (Uniprot ID#P10589)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_11152306
产品详细信息
Recommended positive controls: COUP TF1 tansfected 293T cell.
Predicted reactivity: Mouse (100%), Rat (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The protein encoded by this gene is a nuclear hormone receptor and transcriptional regulator. The encoded protein acts as a homodimer and binds to 5'-AGGTCA-3' repeats. Defects in this gene are a cause of Bosch-Boonstra optic atrophy syndrome (BBOAS).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: avian erythroblastic leukemia viral (v-erb-a) oncogene homolog-like 3; chicken ovalbumin upstream promoter-transcription factor I; COUP transcription factor 1; COUP transcription factor I; COUP-TF I; COUP-TF1; EAR-3; Nuclear receptor subfamily 2 group F member 1; nuclear receptor subfamily 2, group F, member 1; transcription factor COUP 1 (chicken ovalbumin upstream promoter 1, v-erb-a homolog-like 3); V-erbA-related protein 3
基因别名: BBOAS; BBSOAS; COUP-TF1; COUP-TFI; COUPTFA; EAR-3; EAR3; ERBAL3; NR2F1; NR2F2; SVP44; TCFCOUP1; TFCOUP1
UniProt ID: (Human) P10589, (Mouse) Q60632
Entrez Gene ID: (Human) 7025, (Mouse) 13865
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
transcription coactivator activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
zinc ion binding
sequence-specific DNA binding
DNA binding
retinoic acid-responsive element binding
metal ion binding
C4 zinc finger nuclear receptor
negative regulation of transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
signal transduction
intracellular receptor signaling pathway
steroid hormone mediated signaling pathway
neuron migration
transcription, DNA-templated
regulation of transcription, DNA-templated
nervous system development
positive regulation of receptor biosynthetic process
negative regulation of neuron projection development
cerebral cortex regionalization
forebrain development
positive regulation of transcription from RNA polymerase II promoter
