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Product Details
PA5-28033
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 123 and 383 of Human NR2F2
Conjugate
Form
Liquid
Concentration
0.57 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2545509
Product Specific Information
Recommended positive controls: mouse brain.
Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (98%), Xenopus laevis (100%), Pig (100%), Chicken (100%), Sheep (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a member of the steroid thyroid hormone superfamily of nuclear receptors. The encoded protein is a ligand inducible transcription factor that is involved in the regulation of many different genes. Alternate splicing results in multiple transcript variants.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ADP-ribosylation factor related protein 1; Apolipoprotein A-I regulatory protein 1; Apolipoprotein AI regulatory protein 1; apolipoprotein regulatory protein 1; ARP-1; chicken ovalbumin; chicken ovalbumin upstream promoter transcription factor 2; chicken ovalbumin upstream promoter-transcription factor I; COUP transcription factor 2; COUP transcription factor II; COUP-TF II; COUP-TF2; MGC117452; Nuclear receptor subfamily 2 group F member 2; nuclear receptor subfamily 2, group F, member 2
Gene Aliases: 2700033K02Rik; 9430015G03Rik; Aporp1; ARP-1; ARP1; CHTD4; COUP-TF2; COUP-TFII; COUPTFB; COUPTFII; EAR3; NF-E3; NR2F1; NR2F2; SVP40; Tcfcoup2; TFCOUP2
UniProt ID: (Human) P24468, (Mouse) P43135
Entrez Gene ID: (Human) 7026, (Mouse) 11819
retinoic acid binding
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
transcription corepressor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
zinc ion binding
protein homodimerization activity
sequence-specific DNA binding
DNA binding
metal ion binding
C4 zinc finger nuclear receptor
negative regulation of transcription from RNA polymerase II promoter
neuron migration
maternal placenta development
negative regulation of endothelial cell proliferation
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
lipid metabolic process
signal transduction
skeletal muscle tissue development
fertilization
anterior/posterior pattern specification
radial pattern formation
negative regulation of endothelial cell migration
intracellular receptor signaling pathway
forebrain development
response to estradiol
steroid hormone mediated signaling pathway
negative regulation of cyclin-dependent protein serine/threonine kinase activity
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
blood vessel morphogenesis
limb development
placenta blood vessel development
trophoblast giant cell differentiation
regulation of transcription involved in lymphatic endothelial cell fate commitment
in utero embryonic development
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
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