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NRBF2 (nuclear receptor-binding factor 2) modulates transcriptional activation by target nuclear receptors. It is involved in starvation-induced autophagy probably by its association with PI3K complex I (PI3KC3-C1). NRBF2 stabilizes the PI3KC3-C1 assembly and enhances ATG14-linked lipid kinase activity of PIK3C3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Comodulator of PPAR and RXR; comodulator of PPAR and RXR 1; comodulator of PPAR and RXR 2; NRBF-2; nuclear receptor binding factor-2; Nuclear receptor-binding factor 2
基因别名: COPR; COPR1; COPR2; NRBF-2; NRBF2
UniProt ID: (Human) Q96F24
Entrez Gene ID: (Human) 29982