Invitrogen

NRXN1 Polyclonal Antibody

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说明书
实验方案
技术支持

产品信息

PA5-49444

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:2,000
-
产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

KLH conjugated synthetic peptide between 77-110 amino acids from the N-terminal region of human NRXN1.
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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Protein A, Antigen affinity chromatography

保存液

PBS, pH 7.4

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2634898

靶标信息

Neuronal cell surface protein that may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins. May play a role in formation or maintenance of synaptic junctions. May mediate intracellular signaling. May play a role in angiogenesis.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: alpha-latrotoxin receptor (calcium-dependent); DKFZp313P2036; FLJ35941; neurexin 1; Neurexin 1alpha; neurexin I; Neurexin I-alpha; Neurexin I-beta; Neurexin-1; Neurexin-1-alpha; Neurexin-1-beta; non-processed neurexin I-alpha

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基因别名: 1700062G21Rik; 9330127H16Rik; A230068P09Rik; Hs.22998; KIAA0578; mKIAA0578; NRXN1; Nrxn1b; PTHSL2; SCZD17

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UniProt ID: (Human) Q9ULB1, (Mouse) Q9CS84, (Rat) Q63372

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Entrez Gene ID: (Human) 9378, (Mouse) 18189, (Rat) 60391

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功能
receptor activity calcium channel regulator activity calcium ion binding protein binding acetylcholine receptor binding cell adhesion molecule binding neuroligin family protein binding transmembrane signaling receptor activity receptor binding metal ion binding calcium-dependent protein binding
参与通路
vesicle docking involved in exocytosis cell adhesion signal transduction chemical synaptic transmission neurotransmitter secretion synapse assembly learning adult behavior social behavior vocal learning neuromuscular process controlling balance protein heterotetramerization positive regulation of synapse assembly positive regulation of synaptic transmission, glutamatergic prepulse inhibition regulation of insulin secretion involved in cellular response to glucose stimulus vocalization behavior positive regulation of synapse maturation postsynaptic membrane assembly gephyrin clustering involved in postsynaptic density assembly neuroligin clustering involved in postsynaptic membrane assembly postsynaptic density protein 95 clustering positive regulation of excitatory postsynaptic potential regulation of grooming behavior angiogenesis heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules neuron cell-cell adhesion calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules cerebellar granule cell differentiation protein localization to synapse establishment of protein localization negative regulation of filopodium assembly positive regulation of establishment of protein localization to plasma membrane protein complex assembly involved in synapse maturation synaptic vesicle clustering presynaptic membrane assembly gamma-aminobutyric acid receptor clustering NMDA glutamate receptor clustering guanylate kinase-associated protein clustering receptor localization to synapse regulation of N-methyl-D-aspartate selective glutamate receptor activity regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity axon guidance
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