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NUP153 Antibody (PA5-55721) in ICC/IF
Immunofluorescence analysis of NUP153 was performed using 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with NUP153 Rabbit Polyclonal Antibody (Product # PA5-55721) at 5 µg/mL in 0.1% BSA, incubated at 4 degree Celsius overnight and then labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27... View More
产品信息
PA5-55721
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2644893
产品详细信息
Immunogen sequence: SSRASDKDIT VSKNTSLPPL WSPEAERSHS LSQHTATSSK KPAFNLSAFG TLSPSLGNSS ILKTSQLGDS PFYPGKTTYG GAAAAVRQSK LRNTP
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.
靶标信息
Nuclear pore complexes regulate the transport of macromolecules between the nucleus and cytoplasm. They are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. Nucleoporins are glycoproteins found in nuclear pores and contain characteristic pentapeptide XFXFG repeats as well as O-linked N-acetylglucosamine residues oriented towards the cytoplasm. The protein encoded by this gene has three distinct domains: a N-terminal region containing a pore targeting and an RNA-binding domain, a central region containing multiple zinc finger motifs, and a C-terminal region containing multiple XFXFG repeats. Alternative splicing results in multiple transcript variants of this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 153 kDa nucleoporin; nuclear pore complex protein hnup153; Nuclear pore complex protein Nup153; nucleoporin 153kD; nucleoporin 153kDa; Nucleoporin Nup153
基因别名: HNUP153; N153; NUP153
UniProt ID: (Human) P49790
Entrez Gene ID: (Human) 9972
mRNA export from nucleus
tRNA export from nucleus
protein import into nucleus
mitotic nuclear division
mitotic nuclear envelope disassembly
regulation of glucose transport
viral process
protein sumoylation
viral transcription
gene silencing by RNA
viral entry into host cell
negative regulation of RNA export from nucleus
nuclear pore complex assembly
viral penetration into host nucleus
intracellular transport of virus
regulation of cellular response to heat
