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产品信息
PA5-105252
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human NKD1(Accession Q969G9), corresponding to amino acid residues D322-G372.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2853858
产品详细信息
Antibody detects endogenous levels of total NAKED1.
靶标信息
In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1; MIM 164820)-beta-catenin-Tcf signaling pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Dvl-binding protein; hNkd; hNkd1; mNkd; mNkd1; naked cuticle 1 homolog; naked cuticle-1; Naked-1; Protein naked cuticle homolog 1
基因别名: 2810434J10Rik; 9030215G15Rik; Naked1; NKD; NKD1; PP7246
UniProt ID: (Human) Q969G9, (Mouse) Q99MH6
Entrez Gene ID: (Human) 85407, (Rat) 364952, (Mouse) 93960
negative regulation of Wnt signaling pathway
positive regulation of protein catabolic process
negative regulation of canonical Wnt signaling pathway
positive regulation of non-canonical Wnt signaling pathway via JNK cascade
negative regulation of convergent extension involved in axis elongation
positive regulation of Wnt signaling pathway, planar cell polarity pathway
multicellular organism development
spermatogenesis
Wnt signaling pathway
cell differentiation
eye photoreceptor cell differentiation
somatic muscle development
regulation of cell motility involved in somitogenic axis elongation
