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产品信息
PA5-17389
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues surrounding Gln227 of human Naked1
偶联物
形式
Liquid
纯化类型
Antigen affinity chromatography
保存液
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_10980420
产品详细信息
It is not recommended to aliquot this antibody.
靶标信息
In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1; MIM 164820)-beta-catenin-Tcf signaling pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Dvl-binding protein; hNkd; hNkd1; naked cuticle-1; Naked-1; Protein naked cuticle homolog 1
基因别名: Naked1; NKD; NKD1; PP7246
UniProt ID: (Human) Q969G9
Entrez Gene ID: (Human) 85407
eye photoreceptor cell differentiation
somatic muscle development
Wnt signaling pathway
positive regulation of protein catabolic process
negative regulation of canonical Wnt signaling pathway
regulation of cell motility involved in somitogenic axis elongation
positive regulation of non-canonical Wnt signaling pathway via JNK cascade
negative regulation of convergent extension involved in axis elongation
positive regulation of Wnt signaling pathway, planar cell polarity pathway
