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Immunogen sequence: GTTPPIEADT LDSSDAQGGL EPRVEKTRPE PTEVLHACKT QVAELELWLQ QANVAVEPET LNADMQQVLE QQLVGCQAML TEIEHKVAFL LETCKDQGLG DNGATQHEAE ALSLKLKTVK CNLEKVQMML QEKHSEDQ
Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 27%.
The protein encoded by this gene is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus. Several transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: KASH domain-containing protein 2; KASH2; MGC96690; nesprin 2; Nesprin-2; Nuclear envelope spectrin repeat protein 2; Nucleus and actin connecting element protein; polytrophin; Protein NUANCE; spectrin repeat containing, nuclear envelope 2; Synaptic nuclear envelope protein 2; synaptic nuclei expressed gene 2; Syne-2
基因别名: EDMD5; KIAA1011; Nesp2; Nesprin-2; NUA; NUANCE; SYNE-2; SYNE2; TROPH
UniProt ID: (Human) Q8WXH0
Entrez Gene ID: (Human) 23224