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产品信息
PA5-72637
产品规格
种属反应
Zebrafish
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 112-138 amino acids from the Central region of DANRE neurog1
偶联物
形式
Liquid
浓度
0.4 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2718491
靶标信息
Neurogenin 1 is a basic helix-loop-helix (bHLH) proteins are transcription factors involved in determining cell type during development. NeuroG1 is a bHLH protein with dual cell-fate specification roles. It functions during neurogenesis, and it has also been shown to inhibit the differentiation of neural stem cells into astrocytes. NeuroG1 promotes neurogenesis by functioning as a transcriptional activator, yet it inhibits astrocyte differentiation by compartmentalizing the CREB-binding protein transcription complex away from astrocyte differentiation genes and by inhibiting STAT transcription factors essential for gliogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: basic helix-loop-helix transcription factor; NeuroD3; neurogenic differentiation 3; Neurogenic differentiation factor 3; Neurogenin-1; Neurogenin-related protein 1; NGN-1; transcription factor
基因别名: cb260; chunp6899; neurod3; neurog1; NGN-1; ngn1; ngr1; Zath4c; zNgn1
UniProt ID: (Zebrafish) O42606
Entrez Gene ID: (Zebrafish) 30239
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
multicellular organism development
nervous system development
axonal fasciculation
peripheral nervous system development
dorsal spinal cord development
hindbrain morphogenesis
olfactory bulb development
forebrain neuron development
habenula development
neurogenesis
cell differentiation
neuron differentiation
axon regeneration
positive regulation of neuron differentiation
positive regulation of transcription from RNA polymerase II promoter
generation of neurons
neuromast development
anterior lateral line nerve development
posterior lateral line nerve development
peripheral nervous system neuron development
negative regulation of neurogenesis
positive regulation of sequence-specific DNA binding transcription factor activity
olfactory placode development
