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Neurogenin 1 Antibody (PA5-78076) in WB
Neurogenin 1 Polyclonal Antibody detects Neurogenin 1 protein by western blot analysis. A 293T whole cell lysate/extract. B of human NEUROG1-transfected 293T cells.12 % SDS-PAGE. Neurogenin 1 Polyclonal Antibody (Product # PA5-78076) dilution: 1:1,000.
产品信息
PA5-78076
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human Neurogenin 1. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2736210
产品详细信息
Positive Control: human NEUROG1-transfected 293T
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Neurogenin 1 is a basic helix-loop-helix (bHLH) proteins are transcription factors involved in determining cell type during development. NeuroG1 is a bHLH protein with dual cell-fate specification roles. It functions during neurogenesis, and it has also been shown to inhibit the differentiation of neural stem cells into astrocytes. NeuroG1 promotes neurogenesis by functioning as a transcriptional activator, yet it inhibits astrocyte differentiation by compartmentalizing the CREB-binding protein transcription complex away from astrocyte differentiation genes and by inhibiting STAT transcription factors essential for gliogenesis.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: bHLHa6; Class A basic helix-loop-helix protein 6; NeuroD3; Neurogenic basic-helix-loop-helix protein; neurogenic differentiation 3; Neurogenic differentiation factor 3; Neurogenin-1; NGN-1
基因别名: AKA; BHLHA6; Math4C; NEUROD3; NEUROG1; NGN; NGN1
UniProt ID: (Human) Q92886
Entrez Gene ID: (Human) 4762
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
nervous system development
neuron differentiation
positive regulation of exit from mitosis
inner ear morphogenesis
cell fate commitment
positive regulation of neuron differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of sequence-specific DNA binding transcription factor activity
