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Neurokinin 2 Receptor (NK2R) Antibody (ATR-002-200UL) in WB
Western blot analysis of rat hippocampus (lanes 1 and 3) and rat uterus (lanes 2 and 4): - 1,2. Anti-Neurokinin 2 Receptor (NK2R) Antibody (#ATR-002), (1:200).3,4. Anti-Neurokinin 2 Receptor (NK2R) Antibody ,preincubated with Neurokinin 2 Receptor/NK2R Blocking Peptide (#BLP-TR002).
Product Details
ATR-002-200UL
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CHTKETLFMTGDMTHSE, corresponding to amino acid residues 351-367 of rat NK2receptor, Intracellular, N-terminus
Conjugate
Form
Lyophilized
Concentration
0.85 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
Target Information
This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neuropeptide substance K, also referred to as neurokinin A.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 7 transmembrane receptor; Neurokinin A receptor; NK-2 receptor; NK-2R; NK2; SK receptor; SKR; substance K receptor; Substance-K receptor; Tachykinin 2 (substance K) receptor; tachykinin NK-2 receptor; Tachykinin receptor 2
Gene Aliases: Nk2r; Skr; Tac2r; Tacr2
UniProt ID: (Mouse) P30549, (Rat) P16610
Entrez Gene ID: (Mouse) 21337, (Rat) 25007
signal transduction
G-protein coupled receptor signaling pathway
tachykinin receptor signaling pathway
neuropeptide signaling pathway
chemical synaptic transmission
positive regulation of acetylcholine secretion, neurotransmission
intestine smooth muscle contraction
negative regulation of luteinizing hormone secretion
operant conditioning
positive regulation of vascular permeability
positive regulation of ion transport
prolactin secretion
positive regulation of uterine smooth muscle contraction
response to electrical stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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