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产品信息
MA5-41649
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
C1
抗原
Recombinant protein Neurokinin A. The antigen corresponds to amino acid range 98-107 of the target protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
PBS with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2899131
靶标信息
The tachykinins belong to an evolutionary conserved family of peptide neurotransmitters that share the c-terminal sequence Phe-X-Gly-Leu-Met-NH2 and have an established role in neurotransmission. The mammalian tachykinins include substance P, neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma.
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生物信息学
蛋白别名: neurokinin 1; neurokinin 2; neurokinin A; neurokinin alpha; neuromedin L; neuropeptide gamma; neuropeptide K; PPT; preprotachykinin; protachykinin; Protachykinin-1; substance K; substance P; tachykinin 2; tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma)
基因别名: Hs.2563; NK2; NKA; NKNA; NPK; TAC1; TAC2
UniProt ID: (Human) P20366
Entrez Gene ID: (Human) 6863
positive regulation of acute inflammatory response
inflammatory response
positive regulation of cytosolic calcium ion concentration
tachykinin receptor signaling pathway
neuropeptide signaling pathway
cell-cell signaling
chemical synaptic transmission
insemination
long-term memory
regulation of blood pressure
associative learning
detection of abiotic stimulus
response to hormone
negative regulation of heart rate
positive regulation of epithelial cell migration
sensory perception of pain
positive regulation of synaptic transmission, cholinergic
positive regulation of synaptic transmission, GABAergic
response to lipopolysaccharide
positive regulation of renal sodium excretion
response to morphine
positive regulation of action potential
positive regulation of ossification
positive regulation of saliva secretion
response to pain
positive regulation of lymphocyte proliferation
positive regulation of stress fiber assembly
cellular response to nerve growth factor stimulus
positive regulation of corticosterone secretion
