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Neuroligin 3 (extracellular) Polyclonal Antibody

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抗体检测数据 (3)

Neuroligin 3 (extracellular) Antibody in Immunohistochemistry (Frozen) (IHC (F))

Neuroligin 3 (extracellular) Antibody in Immunohistochemistry (Frozen) (IHC (F))

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Neuroligin 3 (extracellular) Antibody (ANR-037-200UL) in IHC (F)

Expression ofNeuroligin-3in ratdeep cerebellar nuclei. Immunohistochemicalstaining of perfusion-fixed frozen rat brain sections with Anti-Neuroligin3 (extracellular) Antibody &(8)239; (#ANR-037), (1:200), followed by goat Anti-rabbit-AlexaFluor-488. A. Neuroligin-3immunoreactivity (green) appearsindeep cerebellar nuclei forming neuronal outlines (arrows).B. Pre-incubation of the Antibody with Neuroligin3 (e... View More

Neuroligin 3 (extracellular) Antibody in Immunohistochemistry (Frozen) (IHC (F))

Neuroligin 3 (extracellular) Antibody in Immunohistochemistry (Frozen) (IHC (F))

Neuroligin 3 (extracellular) Antibody in Western Blot (WB)

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Neuroligin 3 (extracellular) Antibody in Immunohistochemistry (Frozen) (IHC (F)) — Expression ofNeuroligin-3in ratdeep cerebellar nuclei. Immunohistochemicalstaining of perfusion-fixed frozen rat brain sections with Anti-Neuroligin3 (extracellular) Antibody &(8)239; (#ANR-037), (1:200), followed by goat Anti-rabbit-AlexaFluor-488. A. Neuroligin-3immunoreactivity (green) appearsindeep cerebellar nuclei forming neuronal outlines (arrows).B. Pre-incubation of the Antibody with Neuroligin3 (extracellular)Blocking Peptide (BLP-NR037), suppressed staining. Cell nuclei are stained with DAPI (blue).

Neuroligin 3 (extracellular) Antibody in Immunohistochemistry (Frozen) (IHC (F)) — Expression ofNeuroligin-3in ratcerebellum. Immunohistochemicalstaining of perfusion-fixed frozen rat brain sections with Anti-Neuroligin3 (extracellular) Antibody &(8)239; (#ANR-037), (1:200), followed by goat Anti-rabbit-AlexaFluor-488.A.Neuroligin-3immunoreactivity (green) appearsinin the granule layer (GL) and in somepurkinjecells (arrows).B. Pre-incubation of the Antibody with Neuroligin3 (extracellular)Blocking Peptide (BLP-NR037), suppressed staining. Cell nuclei are stained with DAPI (blue).

Neuroligin 3 (extracellular) Antibody in Western Blot (WB) — Western blot analysis of rat (lanes 1 and 3) and mouse (lanes 2 and 4)brain lysate: - 1,2. Anti-Neuroligin 3 (extracellular) Antibody (#ANR-037), (1:200).3,4. Anti-Neuroligin 3 (extracellular) Antibody , preincubated with Neuroligin 3 (extracellular) Blocking Peptide (#BLP-NR037).

产品信息

ANR-037-200UL

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:200

-

免疫组化（冰冻） (IHC (F))

1:200

-

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

(C)SHITRRPNGKTWSTKR, corresponding to amino acid residues 656-671 of rat NLGN3, Extracellular, N-terminus

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.8 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.4, with 1% BSA

内含物

0.05% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

靶标信息

This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: ASPGX1; AUTSX1; Gliotactin homolog; neuroligin 3 protein; Neuroligin-3

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基因别名: A230085M13Rik; HNL3; KIAA1480; NL3; NLGN3

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UniProt ID: (Human) Q9NZ94, (Mouse) Q8BYM5, (Rat) Q62889

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Entrez Gene ID: (Human) 54413, (Mouse) 245537, (Rat) 171297

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receptor activity protein binding neurexin family protein binding cell adhesion molecule binding carboxylic ester hydrolase activity scaffold protein binding cell adhesion molecule

regulation of respiratory gaseous exchange by neurological system process receptor-mediated endocytosis neuron cell-cell adhesion synapse assembly learning visual learning adult behavior social behavior axon extension oligodendrocyte differentiation modulation of synaptic transmission synapse organization positive regulation of synapse assembly positive regulation of synaptic transmission, glutamatergic rhythmic synaptic transmission excitatory postsynaptic potential inhibitory postsynaptic potential long-term synaptic potentiation positive regulation of dendritic spine development negative regulation of dendritic spine morphogenesis vocalization behavior negative regulation of excitatory postsynaptic potential postsynaptic membrane assembly presynaptic membrane assembly positive regulation of inhibitory postsynaptic potential regulation of long-term synaptic potentiation positive regulation of protein localization to synapse regulation of N-methyl-D-aspartate selective glutamate receptor activity regulation of terminal button organization positive regulation of excitatory postsynaptic potential positive regulation of synaptic vesicle clustering positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity cell adhesion regulation of synaptic transmission, glutamatergic regulation of dendritic spine morphogenesis regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity metabolic process