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Alomone Labs, LTD
Nicotinic Acetylcholine Receptor beta 4 (CHRNB4) (extracellular) Polyclonal Antibody
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Nicotinic Acetylcholine Receptor beta 4 (CHRNB4) (extracellular) Antibody (ANC-014-200UL) in ICC/IF
Expression of nAChR beta 4 in rat PC12 cells - Cell surface detection of nAChR beta 4 in live intact rat pheochromocytoma PC12 cells. A. Cells were stained with Anti-Nicotinic Acetylcholine Receptor beta 4 (CHRNB4) (extracellular) Antibody (#ANC-014), (1:100), followed by goat Anti-rabbit-AlexaFluor-594 secondary Antibody (red). B. Cell nuclei were visualized using Hoechst 33342 (blue). C. Merge of the two ... View More
产品信息
ANC-014-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CYEGVNILRIPAKR, corresponding to amino acid residues 95-108 of rat nAChR beta 4, Extracellular, N-terminus
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: acetylcholine receptor; Acetylcholine receptor beta 4; acetylcholine receptor, nicotinic, beta 4 (neuronal); cholinergic receptor; cholinergic receptor, nicotinic beta 4; cholinergic receptor, nicotinic, beta 4 (neuronal); cholinergic receptor, nicotinic, beta polypeptide 4; N-alpha 2; nAChRB4; Neuronal acetylcholine receptor non-alpha-2 chain; Neuronal acetylcholine receptor subunit beta-4; neuronal nicotinic receptor beta 4 subunit; nicotinic acetylcholine receptor beta4 subunit
基因别名: Acrb-4; Acrb4; CHRNB4
UniProt ID: (Human) P30926, (Mouse) Q8R493, (Rat) P12392
Entrez Gene ID: (Human) 1143, (Mouse) 108015, (Rat) 25103
action potential
ion transport
smooth muscle contraction
regulation of smooth muscle contraction
signal transduction
synaptic transmission, cholinergic
locomotory behavior
response to nicotine
behavioral response to nicotine
regulation of neurotransmitter secretion
protein heterooligomerization
positive regulation of transmission of nerve impulse
synaptic transmission involved in micturition
cation transmembrane transport
transport
regulation of membrane potential
cation transport
