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Alomone Labs, LTD
Nicotinic Acetylcholine Receptor beta 4 (CHRNB4) (extracellular) Polyclonal Antibody, Atto™ 594
FIGURE: 1 / 2
Nicotinic Acetylcholine Receptor beta 4 (CHRNB4) (extracellular) Antibody (ANC-014-AR-50UL) in ICC/IF
Expression of nAChR beta 4 in human SH-SY5Y cells - Cell surface detection of nAChR beta 4 in live intact human SH-SY5Y neuroblastoma cells. A. Cells were stained with Anti-Nicotinic Acetylcholine Receptor beta 4 (CHRNB4) (extracellular)-ATTO Fluor-594 Antibody (#ANC-014-AR), (1:100), (red). B. Live image of the cells. C. Merge of the two images.
Product Details
ANC-014-AR-50UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CYEGVNILRIPAKR, corresponding to amino acid residues 95-108 of rat nAChR beta 4, Extracellular, N-terminus
Conjugate
Excitation/Emission Max
602/622 nm
Form
Lyophilized
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 50 µL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: acetylcholine receptor; Acetylcholine receptor beta 4; acetylcholine receptor, nicotinic, beta 4 (neuronal); cholinergic receptor; cholinergic receptor, nicotinic beta 4; cholinergic receptor, nicotinic, beta 4 (neuronal); cholinergic receptor, nicotinic, beta polypeptide 4; N-alpha 2; nAChRB4; Neuronal acetylcholine receptor non-alpha-2 chain; Neuronal acetylcholine receptor subunit beta-4; neuronal nicotinic receptor beta 4 subunit; nicotinic acetylcholine receptor beta4 subunit
Gene Aliases: Acrb-4; Acrb4; CHRNB4
UniProt ID: (Human) P30926, (Mouse) Q8R493, (Rat) P12392
Entrez Gene ID: (Human) 1143, (Mouse) 108015, (Rat) 25103
action potential
ion transport
smooth muscle contraction
regulation of smooth muscle contraction
signal transduction
synaptic transmission, cholinergic
locomotory behavior
response to nicotine
behavioral response to nicotine
regulation of neurotransmitter secretion
protein heterooligomerization
positive regulation of transmission of nerve impulse
synaptic transmission involved in micturition
cation transmembrane transport
transport
regulation of membrane potential
cation transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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