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产品信息
PA5-82096
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2789257
产品详细信息
Immunogen sequence: SLTNTKTGFS VKDILDLPDT NDEEGSVAEG PEEENEGPEP AKRAGPLGQG ALDAVQSLPL KNPFYDSSDN PYTRWLASTE GLQYSLHGLA AGAPPQDSSS KSPEPSADES PDNDKETP
靶标信息
The protein encoded by this gene contains a homeobox domain and may be involved in the morphogenesis of the central nervous system. This gene is found on chromosome 20 near NKX2-4, and these two genes appear to be duplicated on chromosome 14 in the form of TITF1 and NKX2-8. The encoded protein is likely to be a nuclear transcription factor.
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生物信息学
蛋白别名: Homeobox protein NK-2 homolog B; Homeobox protein Nkx-2.2; NK2 transcription factor related, locus 2; NK2 transcription factor-like protein B; Nkx2.2
基因别名: NKX2-2; NKX2.2; NKX2B
UniProt ID: (Human) O95096
Entrez Gene ID: (Human) 4821
type B pancreatic cell development
pancreatic A cell fate commitment
type B pancreatic cell fate commitment
pancreatic PP cell fate commitment
transcription, DNA-templated
smoothened signaling pathway
brain development
response to glucose
oligodendrocyte development
spinal cord motor neuron differentiation
spinal cord oligodendrocyte cell fate specification
optic nerve development
endocrine pancreas development
response to progesterone
negative regulation of neuron differentiation
positive regulation of neuron differentiation
positive regulation of transcription from RNA polymerase II promoter
digestive tract development
neuron fate specification
astrocyte differentiation
positive regulation of oligodendrocyte differentiation
positive regulation of sequence-specific DNA binding transcription factor activity
ventral spinal cord interneuron fate determination
