Invitrogen

Nkx3.1 Monoclonal Antibody (4H4)

查看其他26个Nkx3.1抗体

抗体检测数据 (4)

Nkx3.1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Nkx3.1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Nkx3.1 Antibody (MA5-15618) in IHC (P)

Immunohistochemical analysis of paraffin-embedded human prostate tissues (A, B) using NKX3A monoclonal antibody (Product # MA5-15618) followed with DAB staining.

Nkx3.1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Nkx3.1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Nkx3.1 Antibody in Western Blot (WB)

Nkx3.1 Antibody in Flow Cytometry (Flow)

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Nkx3.1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of paraffin-embedded human prostate tissues (A, B) using NKX3A monoclonal antibody (Product # MA5-15618) followed with DAB staining.

Nkx3.1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of paraffin-embedded human liver tissues using NKX3A monoclonal antibody (Product # MA5-15618).

Nkx3.1 Antibody in Western Blot (WB) — Western blot analysis of NKX3A using NKX3A monoclonal antibody (Product # MA5-15618) in LNCaP (1) cell lysate.

Nkx3.1 Antibody in Flow Cytometry (Flow) — Flow cytometric analysis of PC-3 cells using NKX3A monoclonal antibody (Product # MA5-15618) (green) and negative control (purple).

产品信息

MA5-15618

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

-

免疫组化（石蜡） (IHC (P))

1:200-1:1,000

-

流式细胞分析 (Flow)

1:200-1:400

-

酶联免疫吸附实验 (ELISA)

1:10,000

-

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG2b

分类

Monoclonal

类型

Antibody

克隆号

4H4

抗原

Purified recombinant fragment of human NKX3A expressed in E. Coli.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

Conc. Not Determined

保存液

ascites

内含物

0.03% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_10980327

产品详细信息

MA5-15618 targets NKX3A in indirect ELISA, FACS, IHC, and WB applications and shows reactivity with Human samples.

The MA5-15618 immunogen is purified recombinant fragment of human NKX3A expressed in E. Coli.
.

MA5-15618 detects NKX3A which has a predicted molecular weight of approximately 26.3kDa.

靶标信息

The homeodomain-containing transcription factor NKX3-1 is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3-1 protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Homeobox protein NK-3 homolog A; Homeobox protein Nkx-3.1; NK homeobox, family 3, A; NK3 transcription factor homolog A; NK3 transcription factor related, locus 1; NKX3-1 antibody; prostate-specific ag

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基因别名: BAPX2; NKX3; NKX3-1; NKX3.1; NKX3A

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UniProt ID: (Human) Q99801

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Entrez Gene ID: (Human) 4824

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transcription regulatory region sequence-specific DNA binding transcription factor activity, RNA polymerase II core promoter sequence-specific core promoter binding transcription factor activity, sequence-specific DNA binding androgen receptor activity protein binding transcription factor binding cysteine-type endopeptidase activator activity involved in apoptotic process estrogen receptor activity protein kinase activator activity estrogen receptor binding histone deacetylase binding sequence-specific DNA binding protein self-association transcription regulatory region DNA binding MADS box domain binding

metanephros development somitogenesis positive regulation of protein phosphorylation transcription, DNA-templated regulation of transcription, DNA-templated activation of cysteine-type endopeptidase activity involved in apoptotic process multicellular organism development salivary gland development heart development positive regulation of cell proliferation negative regulation of cell proliferation male gonad development positive regulation of gene expression negative regulation of gene expression positive regulation of cell death positive regulation of phosphatidylinositol 3-kinase signaling androgen receptor signaling pathway activation of protein kinase activity response to testosterone cellular response to drug dorsal aorta development positive regulation of cysteine-type endopeptidase activity involved in apoptotic process protein kinase B signaling negative regulation of insulin-like growth factor receptor signaling pathway negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated negative regulation of mitotic cell cycle positive regulation of mitotic cell cycle positive regulation of transcription from RNA polymerase II promoter branching morphogenesis of an epithelial tube negative regulation of epithelial cell proliferation positive regulation of cell division pharyngeal system development branching involved in prostate gland morphogenesis epithelial cell proliferation involved in salivary gland morphogenesis negative regulation of epithelial cell proliferation involved in prostate gland development cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to steroid hormone stimulus cellular response to hypoxia mitotic cell cycle arrest negative regulation of estrogen receptor binding positive regulation of androgen secretion positive regulation of response to DNA damage stimulus positive regulation of apoptotic signaling pathway positive regulation of intrinsic apoptotic signaling pathway