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Nucleostemin Antibody (PA5-83349) in IHC (P)
Immunohistochemical analysis of Nucleostemin in human tonsil using Nucleostemin Polyclonal Antibody (Product # PA5-83349) shows strong positivity in nucleoli in non-germinal center cells, squamous epithelial cells and germinal center cells with addition cytoplasmic-nuclear positivity.
产品信息
PA5-83349
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.4 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2790505
产品详细信息
Immunogen sequence: KQQQKLDRQK ELEKKRKLET NPDIKPSNVE PMEKEFGLCK TENKAKSGKQ NSKKLYCQEL KKVIEASDVV LE
靶标信息
Arylsulfatase F, also known as ARSF, is a 590 amino acid secretory protein that belongs to the sulfatase family of bone and cartilage matrix proteins. Arylsulfatase F uses calcium as a cofactor to catalyze reactions that are important in maintaining correct bone composition. The activity of Arylsulfatase F, unlike that of other family members, such as Arylsulfatase E, is not inhibited by warfarin. The gene encoding Arylsulfatase F maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: E2-induced gene 3 protein; estradiol-induced nucleotide binding protein; guanine nucleotide binding protein-like 3 (nucleolar); Guanine nucleotide-binding protein-like 3; MGC800; NNP47; Novel nucleolar protein 47; Nucleolar GTP-binding protein 3; Nucleostemin
基因别名: C77032; E2IG3; GNL3; NNP47; NS
UniProt ID: (Human) Q9BVP2
Entrez Gene ID: (Human) 26354
cell proliferation
positive regulation of telomere maintenance
positive regulation of protein sumoylation
regulation of cell proliferation
ribosome biogenesis
positive regulation of pri-miRNA transcription from RNA polymerase II promoter
positive regulation of protein localization to chromosome, telomeric region
