Osenses

OA1 Polyclonal Antibody

OA1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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OA1 Antibody (OSR00146W-100UL) in IHC (P)

IHC-P on paraffin sections of human eye. HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered thru 0.2 µm. Detection was done using Novolink HRP polymer from Leica following manufacturers instructions. Primary antibody: dilution 1:1000, incubated 30 min at RT using Autostainer. Sections were counterstained with Harris Hematoxylin.

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产品信息

OSR00146W-100UL

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:300-1:2,000

免疫组化（石蜡） (IHC (P))

1:1,000

其他PubMed (Misc)

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产品规格

种属反应

Human

已发表种属

Not Applicable

宿主/亚型

Rabbit / Ig

分类

Polyclonal

类型

Antibody

抗原

A synthetic peptide from the 3d cytoplasmic domain of human GPR143 (OA1) conjugated to blue carrier protein was used as the antigen

偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

Conc. Not Determined

保存液

whole serum

内含物

no preservative

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

Specificity of this antibody: OA1.

靶标信息

Ocular albinism type 1 protein is a conserved integral membrane protein with seven transmembrane domains. It is expressed in the eye and epidermal melanocytes. Defects in GPR143 are the cause of ocular albinism type 1 (OA1); also known as Nettleship-Falls type ocular albinism. OA1 is an X-linked disorder characterized by severe impairment of visual acuity, retinal hypopigmentation and the presence of macromelanosomes.

仅用于科研。不用于诊断过程。未经明确授权不得转售。