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产品信息
PA5-101905
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human SLCO1A2(Accession P46721), corresponding to amino acid residues C252-T302.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2851337
产品详细信息
Antibody detects endogenous levels of total SLCO1A2.
靶标信息
The organic anion transporting polypeptides, OATP-A (also designated OATP1, OATP1A2 and SLC21A3) and OATP-C (also designated OATP2, SLC21A6 and LST1), mediate hepatic uptake of cardiac glycosides. The expression of OATP-C, but not OATP-A, is inducible by phenobarbital and pregnenolone-16a-carbonitrile, resulting in the increased capacity of the liver to extract cardiac glycosides from the plasma. OATP-A is expressed in liver and kidney and helps mediate sodium-independent uptake of the anionic steroid conjugates dehydroepiandrosterone sulfate, estradiol-17-glucuronide and prostaglandin. OATP-C is exclusively expressed in liver and is localized to the basolateral hepatocyte membrane.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: OATP-1; OATP-A; OATP1A2; organic anion transporting polypeptide A; Organic anion-transporting polypeptide 1; SO1A2; Sodium-independent organic anion transporter; solute carrier family 21 (organic anion transporter), member 3; Solute carrier family 21 member 3; Solute carrier organic anion transporter family member 1A2; solute carrier organic anion transporter family, member 1A2
基因别名: OATP; OATP-A; OATP1; OATP1A2; SLC21A3; SLCO1A2
UniProt ID: (Human) P46721
Entrez Gene ID: (Human) 6579
