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OATP2/OATP8 Antibody (MA3-935) in ICC/IF
Immunofluorescent analysis of OATP8 in HepG2 Cells. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with a OATP8 monoclonal antibody (Product # MA3-935) at a dilution of 1:20 overnight at 4 C, washed with PBS and incubated with a DyLight-488 conjugated secondary antibody (Product # 35503). OATP8 staining (green), F-Actin staining with ... View More
产品信息
MA3-935
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Not Applicable
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
MDQ
抗原
Synthetic peptide corresponding to residues M(1) D Q N Q H L N K T A E A Q P S E N K K T R Y(23) C of human OATP2.
偶联物
形式
Liquid
浓度
Conc. Not Determined
保存液
tissue culture supernatant
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2254802
产品详细信息
MA3-935 detects OATP8 from human tissue and cells. This antibody does not detect dog, mouse or rat protein. MA3-935 also detects the OATP2 isoform.
MA3-935 has been successfully used in immunohistochemistry, immunofluorescence and immunoprecipitation procedures. Immunofluorescence staining of OATP8 in human liver samples results in a pattern consistent with plasma membrane staining.
The MA3-935 immunogen is a synthetic peptide corresponding ot residues M(1) D Q N Q H L N K T A E A Q P S E N K K T R Y(23) C of human OATP2.
靶标信息
The OATPs (organic anion transporter polypeptides) are a family of transport proteins that have been found to mediate the uptake of organic ions into hepatocyte cells. These proteins fall into the solute carrier family 21A (SLC21A), and are expressed in liver, kidney, and brain. These polypeptides are involved in the excretion of potentially toxic compounds and therefore play a role in the overall detoxification system of the body. Unlike other members of the OATP family, OATP2 and 8 have been detected exclusively in the liver, and there is an 80% amino acid sequence homology between these polypeptides. Other names for OATP2 include SLC21A6, OATP-C, and LST-1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Liver-specific organic anion transporter 1; Liver-specific organic anion transporter 2; liver-specific organic anion transporter 3TM13; LST-1; LST-2; OATP-2; OATP-8; OATP-C; OATP1B3; Organic anion transporter 8; organic anion transporter LST-3c; Organic anion transporter SLC21A6; Organic anion-transporting polypeptide 8; SLCO1B1; Sodium-independent organic anion-transporting polypeptide 2; solute carrier family 21 (organic anion transporter), member 6; solute carrier family 21 (organic anion transporter), member 8; Solute carrier family 21 member 6; Solute carrier family 21 member 8; Solute carrier organic anion transporter family member 1B1; Solute carrier organic anion transporter family member 1B3; solute carrier organic anion transporter family, member 1B1; solute carrier organic anion transporter family, member 1B3
基因别名: HBLRR; LST-1; LST-2; LST-3TM13; LST1; LST2; LST3; OATP-8; OATP-C; OATP1B1; OATP1B3; OATP2; OATP8; OATPC; SLC21A6; SLC21A8; SLCO1B1; SLCO1B3
UniProt ID: (Human) Q9Y6L6, (Human) Q9NPD5
Entrez Gene ID: (Human) 10599, (Human) 28234
