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产品信息
PA5-77217
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant full length Human OAZ1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2720944
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
OAZ1 catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. This protein play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. The protein expression is auto-regulated by polyamine-enhanced translational frameshifting.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: antizyme 1; AZ1; ODC-Az; Ornithine decarboxylase antizyme 1
基因别名: Antizyme; AZ-1; AZ1; AZI; OAZ; OAZ1; ODC-Az; ODCAC
UniProt ID: (Human) P54368, (Mouse) P54369, (Rat) P54370
Entrez Gene ID: (Human) 4946, (Mouse) 18245, (Rat) 25502
regulation of cellular amino acid metabolic process
polyamine biosynthetic process
transport
negative regulation of catalytic activity
positive regulation of protein catabolic process
positive regulation of intracellular protein transport
negative regulation of polyamine transmembrane transport
polyamine metabolic process
negative regulation of protein homodimerization activity
