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产品信息
H00051686-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
OAZ3 (AAH73949.1, 1 a.a. approximately 190 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MTVPWRPGKR RITYKEEEDL TLQPRPASSA PESLVGLQEG KSTEQGNHDQ LKELYSAGNL TVLATDPLLH QDPVQLDFHF RLTSQTSAHW HGLLCDRRLF LDIPYQALDQ GNRESLTATL EYVEEKTNVD SVFVNFQNDR NDRGALLRAF SYMGFEVVRP DHPALPPLDN VIFMVYPLER DVGHLPSEPP
靶标信息
The antizyme family is a group of small proteins that play a role in cell growth and division by regulating the biosynthesis of polyamines such as putrescine, spermidine and spermine. AZ3, also known as OAZ3 (Ornithine decarboxylase antizyme 3), is a 187 amino acid protein that belongs to the ODC antizyme family. AZ3 probably plays a key role in spermatogenesis by regulating the intracellular concentration of polyamines in haploid germ cells because it binds to, and destabilizes, ornithine decarboxylase. However, mutations in the AZ3 gene are not a common cause of male infertility and the normal AZ3 protein does not accelerate ornithine decarboxylase degeneration. AZ3 expression has a sharp onset in early spermatids, peaks in later stages and is gone in spermatozoa.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: antizyme 3; AZ3; ODC-Az 3; Ornithine decarboxylase antizyme 3; testicular secretory protein Li 31
基因别名: AZ3; OAZ-t; OAZ3; TISP15
UniProt ID: (Human) Q9UMX2
Entrez Gene ID: (Human) 51686
