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OCT6 Antibody (PA5-110202) in WB
Western blot analysis of OCT6 in extracts of various cell lines. Samples were incubated with OCT6 Polyclonal antibody (Product # PA5-110202) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-110202
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human POU3F1 (NP_0026903)
偶联物
形式
Liquid
浓度
1.98 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2855613
产品详细信息
Immunogen sequence: MATTAQYLPR GPGGGAGGTG PLMHPDAAAA AAAAAAAERL HAGAAYREVQ KLMHHEWLGA GAGHPVGLAH PQWLPTGGGG GGDWAGGPHL EHGKAGGGGT GRADDGGGGG GFHARLVHQG AAHAGAAWAQ GSTAHHLGPA MSPSPGASGG HQPQPLGLYA QAAYPGGGGG GLAGMLAAGG GGAGPGLHHA LHEDGHEAQL EPSPPPHLGA HGHAHGHAHA GGLHAAAAHL HPGAGGGGSS VGEHSDEDAP SSDDLEQFAK
靶标信息
POU3F1 is a member of the POU domain family of proteins, and regulates events during neurogenesis and myelination.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 6-Oct; Oct-6; octamer binding factor oct6; Octamer-binding protein 6; Octamer-binding transcription factor 6; octoamer transcription factor-6; octomer-6; OTF-6; POU domain transcription factor SCIP; POU domain, class 3, transcription factor 1; suppressed cAMP-inducible POU; Tst-1
基因别名: Oct-6; Oct6; Otf-6; Otf6; Pou3f1; Scip; Test1; Testes-1; Tst-1; Tst1
UniProt ID: (Mouse) P21952, (Rat) P20267
Entrez Gene ID: (Mouse) 18991, (Rat) 192110
RNA polymerase II transcription coactivator activity
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
brain development
epidermis development
positive regulation of gene expression
Schwann cell development
myelination in peripheral nervous system
keratinocyte differentiation
forebrain development
myelination
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of transcription from RNA polymerase II promoter
glial cell differentiation
negative regulation of transcription, DNA-templated
