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OFD1 Antibody (PA5-112634) in IHC (P)
Immunohistochemistry (Paraffin) analysis of OFD1 in paraffin-embedded human skeletal muscle tissue. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30 min at 37°C, then the primary antibody (1% BSA) was incubated at 4°C overnight. The sample was incubated with a OFD1 polyclonal antibody (Product # PA5-... View More
产品信息
PA5-112634
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human Oral-facial-digital syndrome 1 protein (598-771AA)
偶联物
形式
Liquid
浓度
0.45 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C or -80°C if preferred
运输条件
Wet ice
RRID
AB_2867369
靶标信息
This gene is located on the X chromosome and encodes a centrosomal protein. A knockout mouse model has been used to study the effect of mutations in this gene. The mouse gene is also located on the X chromosome, however, unlike the human gene it is not subject to X inactivation. Mutations in this gene are associated with oral-facial-digital syndrome type I and Simpson-Golabi-Behmel syndrome type 2. Many pseudogenes have been identified; a single pseudogene is found on chromosome 5 while as many as fifteen have been found on the Y chromosome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Centriole and centriolar satellite protein OFD1; Oral-facial-digital syndrome 1 protein; Oral-facial-digital syndrome 1 protein homolog; Protein 71-7A
基因别名: 71-7A; CXorf5; DXGgc7e; JBTS10; OFD1; ORF2; RP23; SGBS2
UniProt ID: (Human) O75665, (Mouse) Q80Z25
Entrez Gene ID: (Human) 8481, (Mouse) 237222
G2/M transition of mitotic cell cycle
mitotic nuclear division
centriole replication
cilium morphogenesis
epithelial cilium movement involved in determination of left/right asymmetry
mitotic spindle assembly
embryonic body morphogenesis
cell projection organization
axoneme assembly
negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation
