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产品信息
PA5-82681
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2789837
产品详细信息
Immunogen sequence: LRTCAAKLRP LTASQTVKTF SQNRPAAART FQQIRCYSAP VAAEPFLSGT SSNYVEEMYC AWLENPKSV
靶标信息
This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitocondrial matrix and uses thiamine pyrophosphate as a cofactor. A congential deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 2-oxoglutarate dehydrogenase complex component E1; 2-oxoglutarate dehydrogenase, mitochondrial; Alpha-ketoglutarate dehydrogenase; Alpha-KGDH-E1; E1o; OGDC-E1; oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide); oxoglutarate decarboxylase; oxoglutarate dehydrogenase (succinyl-transferring); testicular tissue protein Li 131; Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase
基因别名: AKGDH; E1k; OGDC; OGDH
UniProt ID: (Human) Q02218
Entrez Gene ID: (Human) 4967
generation of precursor metabolites and energy
glycolytic process
tricarboxylic acid cycle
2-oxoglutarate metabolic process
succinyl-CoA metabolic process
lysine catabolic process
NADH metabolic process
cerebellar cortex development
striatum development
hippocampus development
thalamus development
pyramidal neuron development
tangential migration from the subventricular zone to the olfactory bulb
glyoxylate metabolic process
olfactory bulb mitral cell layer development
