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产品信息
PA5-20369
产品规格
种属反应
Human,
Mouse
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 15 amino acid peptide from near the carboxy terminus of human ORAI2.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_11152055
产品详细信息
A suggested positive control is Jurkat cell lysate.
PA5-20369 can be used with blocking peptide PEP-0486.
靶标信息
Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI2 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. Like ORAI1, ORAI2 has been shown to function as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor, although at a lesser efficacy than ORAI1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: calcium release-activated calcium channel 2; CAP-binding protein complex interacting protein 2; CAP-binding protein complex-interacting protein 2; H_NH0514P08.8; Protein orai-2; putative protein ORAI2-2; Transmembrane protein 142B
基因别名: A730041O15Rik; C7orf19; CBCIP2; MEM142B; ORAI2; PP1729; TMEM142B
UniProt ID: (Human) Q96SN7, (Mouse) Q8BH10
Entrez Gene ID: (Human) 80228, (Mouse) 269717
