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产品信息
MA5-15778
产品规格
种属反应
Human,
Rat
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
2H2G9
抗原
A 19 amino acid peptide from near the carboxy terminus of human ORAI3.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_11156221
产品详细信息
A suggested positive control is rat spleen tissue lysate.
靶标信息
ORAI3 is a protein coding gene that is involved in calcium signaling and regulation of calcium homeostasis. It is a member of the ORAI family of proteins that form calcium release-activated calcium (CRAC) channels in the plasma membrane of cells. These channels are activated by depletion of calcium from the endoplasmic reticulum, leading to an influx of calcium ions into the cytoplasm. ORAI3 has been implicated in a variety of physiological processes, including T-cell activation, muscle contraction, and neurotransmitter release. Dysregulation of ORAI3 expression or function has been associated with various diseases, including immune disorders, cancer, and cardiovascular disease
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生物信息学
蛋白别名: calcium release-activated calcium modulator 3 protein; Protein orai-3; Transmembrane protein 142C
基因别名: ORAI3; RGD1306538; TMEM142C
UniProt ID: (Human) Q9BRQ5, (Rat) Q6AXR8
Entrez Gene ID: (Human) 93129, (Rat) 309000
